NCIt synonyms : PIG-A; GPI3; Paroxysmal Nocturnal Hemoglobinuria Gene; Phosphatidylinositol Glycan, Class A (Paroxysmal Nocturnal Hemoglobinuria) Gene; Phosphatidylinositol Glycan Anchor Biosynthesis Class A wt Allele; Phosphatidylinositol Glycan Anchor Biosynthesis, Class A Gene; MCAHS2; PNH1;
NCIt definition : Human PIGA wild-type allele is located in the vicinity of Xp22.1 and is approximately
16 kb in length. This allele, which encodes phosphatidylinositol N-acetylglucosaminyltransferase
subunit A protein, plays a role in the modulation of protein lipidation. Mutation
of the gene is associated with paroxysmal nocturnal hemoglobinuria.;