MAGI2 wt Allele

Preferred Label : MAGI2 wt Allele;

NCIt synonyms : MAGI-2; Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 2 wt Allele; ARIP1; SSCAM; ACVRINP1; AIP1; ACVRIP1; KIAA0705; AIP-1;

NCIt definition : Human MAGI2 wild-type allele is located in the vicinity of 7q21 and is approximately 1436 kb in length. This allele, which encodes membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, is involved in the modulation of synaptic receptor localization.;

NCIt note : Rearrangements of the MAGI2 gene, which inactivate the gene, were found in prostate cancers. (Nature 2011: 470; 214-220.);

GenBank Accession Number : AB014605;

Details

Origin ID

C95813;

UMLS CUI

C3272369;

OMIM relation
- Membrane-associated guanylate kinase, ww and pdz domains-containing, 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 7q21 [NCIt concept]
gene_is_element_in_pathway
- Tight Junction Assembly Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients