" /> Emibetuzumab - CISMeF





Preferred Label : Emibetuzumab;

NCIt synonyms : Anti-c-MET Monoclonal Antibody LY2875358;

NCIt definition : A humanized IgG4 monoclonal antibody directed against human hepatocyte growth factor receptor (HGFR or c-MET) with potential antineoplastic activity. Emibetuzumab binds to c-MET, thereby preventing the binding of HGF to its receptor c-Met and subsequent activation of the HGF/c-Met signaling pathway. This may result in cell death in c-Met-expressing tumor cells. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays a key role in cancer cell growth, survival, angiogenesis, invasion, and metastasis.;

UNII : MO4K3GDN1I;

CAS number : 1365287-97-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1365287-97-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : LY2875358; LA-480;

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10/05/2024


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