" /> JAK2 Inhibitor BMS-911543 - CISMeF





Preferred Label : JAK2 Inhibitor BMS-911543;

NCIt related terms : BMS-911543;

NCIt definition : An orally available small molecule targeting a subset of Janus-associated kinase (JAK) with potential antineoplastic activity. JAK2 inhibitor BMS-911543 selectively inhibits JAK2, thereby preventing the JAK/STAT (signal transducer and activator of transcription) signaling cascade, including activation of STAT3. This may lead to an induction of tumor cell apoptosis and a decrease in cellular proliferation. JAK2, often upregulated or mutated in a variety of cancer cells, mediates STAT3 activation and plays a key role in tumor cell proliferation and survival.;

UNII : 7N03P021J8;

InChIKey : JCINBYQJBYJGDM-UHFFFAOYSA-N;

CAS number : 1271022-90-2;

Molecule name : BMS-911543; BMS 911543;

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28/07/2025


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