Dentin Matrix Acidic Phosphoprotein 1

Preferred Label : Dentin Matrix Acidic Phosphoprotein 1;

NCIt synonyms : DMP-1; Dentin Matrix Protein 1; Dentin Matrix Acidic Phosphoprotein;

NCIt definition : Dentin matrix acidic phosphoprotein 1 (513 aa, 56 kDa) is encoded by the human DMP1 gene. This protein plays a role in the activation of osteoblast-specific genes and the nucleation of hydroxyapatite.;

NCIt note : Dentin matrix acidic phosphoprotein 1 may have therapeutic use as an anti-angiogenic agent. (Blood, 2010; DOI: 10.1182/blood-2010-08-298810.);

Details

Origin ID

C95577;

UMLS CUI

C1531071;

OMIM relation
- Dentin matrix acidic phosphoprotein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- DMP1 protein, human [MeSH concept]
- DMP1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DMP1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_expressed_in_tissue
- Tooth [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Organogenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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