GRPR wt Allele

Preferred Label : GRPR wt Allele;

NCIt synonyms : Gastrin-Releasing Peptide Receptor Gene; BB2; Gastrin Releasing Peptide Receptor wt Allele; BB2R; BRS2;

NCIt definition : Human GRPR wild-type allele is located in the vicinity of Xp22.2 and is approximately 30 kb in length. This allele, which encodes gastrin-releasing peptide receptor protein, is involved in the modulation of both cell proliferation and gastrin-mediated signaling. Aberrant expression of the gene is associated with several cancers.;

GenBank Accession Number : NM_005314;

Details

Origin ID

C95066;

UMLS CUI

C2986884;

Automatic exact mappings (from CISMeF team)
- Intercellular adhesion molecule 1 [ORDO Gene]
- Intercellular adhesion molecule 1 [OMIM gene]
OMIM relation
- Gastrin-releasing peptide receptor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- Xp22.2 [NCIt concept]
gene_is_element_in_pathway
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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