XRN1 wt Allele

Preferred Label : XRN1 wt Allele;

NCIt synonyms : DKFZp686B22225; SEP1; DKFZp686F19113; FLJ41903; DKFZp434P0721; 5'-3' Exoribonuclease 1 wt Allele;

NCIt definition : Human XRN1 wild-type allele is located in the vicinity of 3q23 and is approximately 141 kb in length. This allele, which encodes 5'-3' exoribonuclease 1 protein, is involved in the regulation of both RNA processing and mRNA stability.;

NCIt note : The XRN1 gene may act as a suppressor of osteogenic sarcoma. (Gene 2002; 298: 121-127.);

GenBank Accession Number : AY137776;

Details

Origin ID

C94706;

UMLS CUI

C2986639;

OMIM relation
- 5-prime,3-prime-exoribonuclease 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3q23 [NCIt concept]
gene_is_element_in_pathway
- RNA Degradation Pathway [NCIt concept]
gene_plays_role_in_process
- Hydrolysis [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Degradation [NCIt concept]
- RNA Processing [NCIt concept]

Keyword's position in hierarchy(ies) :

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