Vindesine Sulfate

Preferred Label : Vindesine Sulfate;

NCIt synonyms : Vindesini Sulfas; Vindesine Sulphate; Desacetyl Vinblastine Amide Sulfate;

NCIt definition : The sulfate salt form of Vindesine. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI);

UNII : CPH2U7DNDY;

InChIKey : COFJBSXICYYSKG-OAUVCNBTSA-N;

CAS number : 59917-39-4;

Drug name : Enison; Eldisin; Gesidine; Eldisine; Eldesine; Fildesin;

Molecule name : LY-099094; LY 099094;

Chemical formula : C43H55N5O7.H2O4S;

NSC code : 245467;

ChEBI ID : CHEBI:32295;

Codes from synonyms : NSC0245467;

Details

Origin ID

C935;

UMLS CUI

C0042683;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Vindesine Sulfate [MeSH concept]
- Vindesine sulfate (substance) [SNOMED CT concept]
- vincaleukoblastine, 3-(aminocarbonyl)-o4-deacetyl-3-de(methoxycarbonyl)-, sulfate (1:1) (salt) [Substance BNPC]
Validated automatic mappings to NTBT
- vindesine [Substance BNPC]
- vindesine [MeSH Descriptor]
chemical_or_drug_has_mechanism_of_action
- Microtubule Process [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Vindesine [NCIt concept]
is_component_of_chemotherapy_regimen
- DVM Regimen [NCIt concept]
is_salt_form_of
- Vindesine [NCIt concept]

Keyword's position in hierarchy(ies) :

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