" /> Vindesine - CISMeF





Preferred Label : Vindesine;

NCIt synonyms : 3-(Aminocarbonyl)-O4-deacetyl-3-de-(methoxycarbonyl)vincaleukoblastine; VDS; DAVA; Deacetylvinblastine Carboxamide; Deacetyl Vinblastine Carboxamide; Desacetylvinblastine Amide; DVA; Compound 112531;

NCIt definition : A synthetic derivative of vinblastine, a naturally occurring vinca alkaloid. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of plant drugs called vinca alkaloids.;

UNII : RSA8KO39WH;

InChIKey : HHJUWIANJFBDHT-ZVTSDNJWSA-N;

CAS number : 53643-48-4;

Molecule name : Lilly CT-3231;

Chemical formula : C43H55N5O7;

ChEBI ID : CHEBI:36373;

Codes from synonyms : NSC0245467; CDR0000045247; 538;

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28/05/2025


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