CD276 wt Allele

Preferred Label : CD276 wt Allele;

NCIt synonyms : 4Ig-B7-H3; UNQ309/PRO352; B7H3; B7-H3; CD276 Antigen Gene; CD276 Molecule wt Allele; PSEC0249; B7RP-2;

NCIt definition : The CD276 wild-type allele is located within 15q23-q24 and is approximately 30 kb in length. This allele, which encodes CD276 antigen protein, plays a role in regulation of both the immune response and T cell proliferation.;

NCIt note : The B7-H3 locus underwent genomic duplication leading to tandemly repeated immunoglobulin-like V and C domains (VC domains). The dominantly expressed human B7-H3 isoform contains tandemly duplicated VC domains. (UniProt);

GenBank Accession Number : AF302102;

Details

Origin ID

C93064;

UMLS CUI

C2985419;

OMIM relation
- Cd276 antigen [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 15q23-q24 [NCIt concept]
gene_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Immune Response Process [NCIt concept]
- T-Cell Activation [NCIt concept]
- T-Cell Proliferation [NCIt concept]

Keyword's position in hierarchy(ies) :

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