NCIt definition : An orally active and small molecule inhibitor of heat shock protein 90 (Hsp90) with
potential antineoplastic activity. Hsp90 inhibitor Debio 0932 specifically blocks
Hsp90, thereby inhibiting its chaperone function and promoting the degradation of
its client proteins, many of which are oncogenic signaling proteins involved in tumor
cell proliferation and survival. This may lead to an inhibition of tumor cell proliferation.
Hsp90, a chaperone protein upregulated in a variety of tumor cells, regulates the
folding, stabilization and degradation of many oncogenic signaling proteins.;
UNII : 0V278OKN9G;
CAS number : 1061318-81-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1061318-81-7
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