" /> Heat Shock Protein 90 - CISMeF





Preferred Label : Heat Shock Protein 90;

NCIt synonyms : HSP-90; HSP90; Heat Shock Protein-90;

NCIt definition : A family of structurally related proteins that play a role in cell signalling, protein folding and cellular stress responses. The members of this family are approximately 90 kDa.;

NCIt note : The Heat Shock Protein 90 members HSP89-alpha and HSP89-beta are a class of cytoplasmic molecular chaperone homodimers that act in the signal transduction mechanism of steroid receptors and may have ATPase activity. CDC37 and HSP90 associate preferentially with CDK4 not bound to type D cyclins. HSPA8, HSP90A, CXCR4, and GDF5 on monocytes form an activation cluster after LPS ligation and are involved in LPS signal transduction. (OMIM 140571, Swiss-Prot P07900, P08238);

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31/07/2025


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