Vancomycin - CISMeF

Preferred Label : Vancomycin;

NCIt definition : A branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci. At a site different from that of penicillins and cephalosporins, vancomycin binds tightly to the D-alanyl-D-alanine portion of cell wall precursors, thereby interfering with bacterial cell wall synthesis. This leads to activation of bacterial autolysins that destroy the cell wall by lysis. Vancomycin may also alter the permeability of bacterial cytoplasmic membranes and may selectively inhibit RNA synthesis.;

Alternative definition : NCI-GLOSS: An antibiotic drug used to fight resistant bacterial infections.;

UNII : 6Q205EH1VU;

InChIKey : MYPYJXKWCTUITO-LYRMYLQWSA-N;

CAS number : 1404-90-6;

Chemical formula : C66H75Cl2N9O24;

ChEBI ID : CHEBI:28001;

Codes from synonyms : CDR0000045246;

Details

Origin ID

C925;

UMLS CUI

C0042313;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Antibiotic [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing vancomycin (medicinal product) [SNOMED CT concept]
- Vancomycin [ICD-11 Extension code]
- Vancomycin [LOINC component]
- Vancomycin (substance) [SNOMED CT concept]
- vancomycin [ATC Code]
- vancomycin [ATC Code]
- vancomycin [Substance BNPC]
- vancomycin [ATC Code]
- vancomycin [SNOMED Notion]
- vancomycin [MeSH concept]
- vancomycin [MeSH Descriptor]
Validated automatic mappings to BTNT
- vancomycin [ATC Code]
- vancomycin [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Vancomycin Hydrochloride [NCIt concept]
is_component_of_chemotherapy_regimen
- Gentamicin/Piperacillin/Vancomycin [NCIt concept]
- Piperacillin/Tazobactam/Vancomycin [NCIt concept]
is_free_acid_or_base_form_of
- Vancomycin Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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