NCIt related terms : JMML; Juvenile Chronic Myelomonocytic Leukemia;
NCIt definition : A clonal myeloid disorder of childhood previously classified as myelodysplastic/myeloproliferative
neoplasm. It is characterized by the presence of monocytic proliferation in peripheral
blood, less than 20% blasts in bone marrow and peripheral blood, splenomegaly, and
the absence of BCR-ABL1 fusion. Almost all patients carry mutations of the RAS pathway.;
Alternative definition : NICHD: A myelodysplastic/myeloproliferative neoplasm of childhood that is principally
characterized by proliferation of the granulocytic and monocytic lineages.; NCI-GLOSS: A rare form of childhood leukemia in which cancer cells often spread into
tissues such as the skin, lung, and intestines.;
Neoplastic status : Malignant;
ICD-O code : 9946/3;
Codes from synonyms : CDR0000045048; CDR0000450126; 10023249;