Juvenile Myelomonocytic Leukemia

Preferred Label : Juvenile Myelomonocytic Leukemia;

NCIt synonyms : JCML; Juvenile Chronic Myelogenous Leukemia; Juvenile Chronic Myeloid Leukemia;

NCIt related terms : JMML; Juvenile Chronic Myelomonocytic Leukemia;

NCIt definition : A clonal myeloid disorder of childhood previously classified as myelodysplastic/myeloproliferative neoplasm. It is characterized by the presence of monocytic proliferation in peripheral blood, less than 20% blasts in bone marrow and peripheral blood, splenomegaly, and the absence of BCR-ABL1 fusion. Almost all patients carry mutations of the RAS pathway.;

Alternative definition : NICHD: A myelodysplastic/myeloproliferative neoplasm of childhood that is principally characterized by proliferation of the granulocytic and monocytic lineages.; NCI-GLOSS: A rare form of childhood leukemia in which cancer cells often spread into tissues such as the skin, lung, and intestines.;

Neoplastic status : Malignant;

ICD-O code : 9946/3;

Codes from synonyms : CDR0000045048; CDR0000450126; 10023249;

Détails

Origin ID

C9233;

UMLS CUI

C0349639;

Automatic exact mappings (from CISMeF team)
- Chronic myelomonocytic leukemia [MedDRA LLT]
- Chronic myelomonocytic leukemia [ICD-10 Sub-category]
- Chronic myelomonocytic leukemia [HPO term]
- Chronic myelomonocytic leukemia [ORDO Disease]
- Chronic myelomonocytic leukemia [PASCAL descriptor]
- Chronic myelomonocytic leukemia (disorder) [SNOMED CT concept]
- Chronic myelomonocytic leukemia (morphologic abnormality) [SNOMED CT concept]
- Juvenile chronic myeloid leukemia [MedDRA LLT]
- Juvenile chronic myeloid leukemia (disorder) [SNOMED CT concept]
- Juvenile myelomonocytic leukaemia [ICD-11 Category]
- Juvenile myelomonocytic leukemia [ICD-10 Sub-category]
- chronic myelomonocytic leukemia [DO Concept]
- leukemia, myelomonocytic, chronic [MeSH concept]
- leukemia, myelomonocytic, chronic [MeSH Descriptor]
Currated CISMeF NLP mapping
- Juvenile chronic myelomonocytic leukaemia [MedDRA Preferred Term]
- Juvenile myelomonocytic leukaemia [ICD-11 Category]
- Juvenile myelomonocytic leukemia [ICD-O code]
- Juvenile myelomonocytic leukemia [HPO term]
- Juvenile myelomonocytic leukemia [OMIM Phenotype]
- Juvenile myelomonocytic leukemia [ORDO Disease]
- Juvenile myelomonocytic leukemia (disorder) [SNOMED CT concept]
- Juvenile myelomonocytic leukemia (morphologic abnormality) [SNOMED CT concept]
- juvenile myelomonocytic leukemia [DO Concept]
- juvenile myelomonocytic leukemia [Disease (Nov.)]
- leukemia, myelomonocytic, juvenile [MeSH Descriptor]
- leukemia, myelomonocytic, juvenile [MeSH concept]
DO Cross reference
- juvenile myelomonocytic leukemia [DO Concept]
Disease may have findings
- Absence of Bone Marrow Dysplasia [NCIt concept]
- Elevated Serum Lysozyme [NCIt concept]
- Fatigue [NCIt concept]
- Fever [NCIt concept]
- Hemoglobin F Increased [NCIt concept]
- Hemorrhage [NCIt concept]
- Hepatomegaly [NCIt concept]
- Nucleated Red Blood Cells Present [NCIt concept]
- Polyclonal Hypergammaglobulinemia [NCIt concept]
- Skin Rash [NCIt concept]
- Splenomegaly [NCIt concept]
- Thrombocytopenia [NCIt concept]
Has associated anatomic sites
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Juvenile chronic myeloid leukaemia [MedDRA LLT]
- Juvenile chronic myeloid leukemia [MedDRA LLT]
- Juvenile chronic myeloid leukemia (disorder) [SNOMED CT concept]
- Juvenile chronic myelomonocytic leukaemia [MedDRA Preferred Term]
- Juvenile chronic myelomonocytic leukemia [MedDRA LLT]
- Juvenile myelomonocytic leukaemia [ICD-11 Category]
- Juvenile myelomonocytic leukemia [ORDO Disease]
- Juvenile myelomonocytic leukemia [OMIM Phenotype]
- Juvenile myelomonocytic leukemia [ICD-O code]
- Juvenile myelomonocytic leukemia [ICD-10 Sub-category]
- Juvenile myelomonocytic leukemia [HPO term]
- Juvenile myelomonocytic leukemia (disorder) [SNOMED CT concept]
- Juvenile myelomonocytic leukemia (morphologic abnormality) [SNOMED CT concept]
- juvenile chronic myelomonocytic leukaemia [SNOMED Notion]
- juvenile myelomonocytic leukemia [DO Concept]
- juvenile myelomonocytic leukemia [Disease (Nov.)]
- leukemia, myelomonocytic, juvenile [MeSH concept]
- leukemia, myelomonocytic, juvenile [MeSH Descriptor]
concept_is_in_subset
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCI CTEP SDC Myelodysplastic/Myeloproliferative Disease Sub-Category Terminology [NCIt concept]
- NCI CTEP Simplified Disease Classification Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Hematology-Oncology Terminology [NCIt concept]
disease_excludes_finding
- Auer Rods Present [NCIt concept]
- Benign Cellular Infiltrate [NCIt concept]
disease_excludes_molecular_abnormality
- BCR-ABL1 Fusion Protein Expression [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Myeloid Cell [NCIt concept]
disease_has_associated_disease
- Anemia [NCIt concept]
disease_has_associated_gene
- NRAS Gene [NCIt concept]
- NRAS wt Allele [NCIt concept]
- PTPN11 Gene [NCIt concept]
- PTPN11 wt Allele [NCIt concept]
disease_has_finding
- Blasts Under 20 Percent of Bone Marrow Nucleated Cells [NCIt concept]
- Blasts Under 20 Percent of Peripheral Blood White Cells [NCIt concept]
- Childhood Lesion [NCIt concept]
- Hypercellular Bone Marrow [NCIt concept]
- Immature Granulocytes in Peripheral Blood Increased [NCIt concept]
- Leukocytosis [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Monocytosis [NCIt concept]
- RAS Signal Transduction Pathway Activated [NCIt concept]
- Splenomegaly [NCIt concept]
disease_has_normal_cell_origin
- Bone Marrow Stem Cell [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic Tissue [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_may_have_associated_disease
- Bronchitis [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Monosomy 7 [NCIt concept]
disease_may_have_molecular_abnormality
- KRAS Gene Mutation [NCIt concept]
- NRAS Gene Mutation [NCIt concept]
- PTPN11 Gene Mutation [NCIt concept]
- RRAS Gene Mutation [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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