BCL11B wt Allele

Preferred Label : BCL11B wt Allele;

NCIt synonyms : hRIT1-alpha; Zinc Finger Protein hRit1 Alpha Gene; CTIP-2; ATL1-alpha; ZNF856B; CTIP2; RIT1; IDDFSTA; ATL1-delta; B-Cell CLL/Lymphoma 11B Gene; ATL1-gamma; IMD49; BAF Chromatin Remodeling Complex Subunit BCL11B wt Allele; ATL1; SMARCM2; ATL1-beta; B-Cell CLL/Lymphoma 11B (Zinc Finger Protein) Gene;

NCIt definition : Human BCL11B wild-type allele is located in the vicinity of 14q32.2 and is approximately 102 kb in length. This allele, which encodes B-cell lymphoma/leukemia 11B protein, may be involved in the mediation of T cell differentiation, tumor suppression and p53-mediated signaling. Aberrant expression is associated with adult T-cell leukemia/lymphoma.;

GenBank Accession Number : AJ404614;

Details

Origin ID

C91856;

UMLS CUI

C2984594;

OMIM relation
- Baf chromatin remodeling complex subunit bcl11b [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 14q32.2 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Acute Leukemia of Ambiguous Lineage with BCL11B Rearrangement [NCIt concept]
- Early T Precursor Acute Lymphoblastic Leukemia with BCL11B Rearrangement [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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