Acute Leukemia of Ambiguous Lineage with BCL11B Rearrangement

Preferred Label : Acute Leukemia of Ambiguous Lineage with BCL11B Rearrangement;

NCIt definition : A rare acute leukemia of ambiguous lineage characterized by the presence of BCL11B gene rearrangement.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1922655;

Details

Origin ID

C203437;

UMLS CUI

C5909250;

Disease may have findings
- Granulocytopenia [NCIt concept]
- Ineffective Hematopoiesis [NCIt concept]
- Thrombocytopenia [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Has cytogenetic abnormalities
- BCL11B Gene Rearrangement [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Chronic Clinical Course [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Leukemic Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Blast [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
- Recurrent Genetic Abnormalities Present [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Multipotent Bone Marrow Stem Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_mapped_to_gene
- BCL11B Gene [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]
pathogenesis_of_disease_involves_gene
- BCL11B Gene [NCIt concept]
- BCL11B wt Allele [NCIt concept]

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