P-cadherin Antagonist PF-03732010

Preferred Label : P-cadherin Antagonist PF-03732010;

NCIt related terms : PF-03732010;

NCIt definition : An agent that inhibits P-cadherin (cdh3), with potential antineoplastic activity. PF-03732010 binds to and inhibits the activity of p-cadherin. Inhibition of the activity of p-cadherin may inhibit tumor cell invasion and proliferation in p-cadherin expressing tumor cells. P-cadherin, a cell-surface protein and member of the cadherin family, is overexpressed in a variety of solid tumors, and plays a role in cell adhesion, motility, invasion and proliferation.;

UNII : LPW79O1J5Z;

CAS number : 2070913-84-5;

Molecule name : PF-03732010;

Details

Origin ID

C91723;

UMLS CUI

C2984514;

Currated CISMeF NLP mapping
- PF 03732010 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PF 03732010 [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Cadherin-3 [NCIt concept]

Keyword's position in hierarchy(ies) :

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