" /> Zanolimumab - CISMeF





Preferred Label : Zanolimumab;

NCIt synonyms : Anti-CD4 Monoclonal Antibody HuMax; HuMax-CD4;

NCIt definition : A human IgG1k monoclonal antibody against the CD4 receptor on T-lymphocytes, with potential antineoplastic and immunosuppressing activities. Zanolimumab targets and binds to the CD4 receptor on certain T-cells thereby preventing the interaction between the CD4 receptor and the major histocompatibility complex class II molecule. This prevents activation of CD4 positive T cells. In addition, zanolimumab is able to induce an antibody-dependent cellular cytotoxicity (ADCC) response against CD4-expressing tumor cells. CD4, a receptor located on a subset of T-lymphocytes, is upregulated in T-cell lymphomas.;

UNII : HG3L8885M0;

CAS number : 652153-01-0;

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08/05/2025


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