Zorubicin - CISMeF

Preferred Label : Zorubicin;

NCIt synonyms : Benzoic Acid Hydrazide 3-Hydrazone with Daunorubicin; (2S-cis)-Benzoic Acid[1-[4-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide; Benzoylhydrazone Daunorubicin; Daunomycin Benzoylhydrazone; Rubidazone; Rubidazon;

NCIt definition : A benzoylhydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis.;

UNII : V25F9362OP;

InChIKey : FBTUMDXHSRTGRV-BJISBDEGSA-N;

CAS number : 54083-22-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 54083-22-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C34H35N3O10;

Details

Origin ID

C91365;

UMLS CUI

C0206788;

Automatic exact mappings (from CISMeF team)
- Zorubicin [ICHI extension code]
- rubidazone [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Zorubicin [ICD-11 Extension code]
- zorubicin [ATC Code]
- zorubicin [MeSH concept]
- zorubicin [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- zorubicin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Zorubicin Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Zorubicin Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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