Preferred Label : Zorubicin Hydrochloride;
NCIt synonyms : Benzoyl Hydrazone Daunorubicin; Daunorubicin Benzoylhydrazone Hydrochloride; Zorubicin; (2S-cis)-Benzoic Acid[1-[4-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3-naphthacenyl]ethylidene]hydrazide;
NCIt related terms : Rubidazone; RP 22050;
NCIt definition : A benzoyl-hydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin.
Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting
DNA replication and repair and RNA and protein synthesis. (NCI04);
UNII : WXM8D9M6DE;
InChIKey : NKFHKYQGZDAKMX-QMFNWPJUSA-N;
CAS number : 36508-71-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 36508-71-1
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G-SRS /a ;
Drug name : Rubidazone;
Molecule name : RP 22,050 Hydrochloride;
Chemical formula : C34H35N3O10.ClH;
NSC code : 164011;
Codes from synonyms : NSC0164011;
Origin ID : C1458;
UMLS CUI : C0874165;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- has_free_acid_or_base_form
- is_component_of_chemotherapy_regimen
- is_salt_form_of
