Zorubicin Hydrochloride

Preferred Label : Zorubicin Hydrochloride;

NCIt synonyms : Benzoyl Hydrazone Daunorubicin; Daunorubicin Benzoylhydrazone Hydrochloride; Zorubicin; (2S-cis)-Benzoic Acid[1-[4-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3-naphthacenyl]ethylidene]hydrazide;

NCIt related terms : Rubidazone; RP 22050;

NCIt definition : A benzoyl-hydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. (NCI04);

UNII : WXM8D9M6DE;

InChIKey : NKFHKYQGZDAKMX-QMFNWPJUSA-N;

CAS number : 36508-71-1;

Drug name : Rubidazone;

Molecule name : RP 22,050 Hydrochloride;

Chemical formula : C34H35N3O10.ClH;

NSC code : 164011;

Codes from synonyms : NSC0164011;

Details

Origin ID

C1458;

UMLS CUI

C0874165;

Automatic exact mappings (from CISMeF team)
- RP 22050 [MeSH concept]
- Zorubicin [ICHI extension code]
- zorubicin [ATC Code]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
Validated automatic mappings to NTBT
- Zorubicin [ICD-11 Extension code]
- zorubicin [MeSH Supplementary Concept]
- zorubicin [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Zorubicin [NCIt concept]
is_component_of_chemotherapy_regimen
- Asparaginase/Cyclophosphamide/Methotrexate/Prednisone/Vincristine/Zorubicin [NCIt concept]
- Cyclophosphamide/Prednisone/Vincristine/Zorubicin [NCIt concept]
- Cytarabine/Zorubicin [NCIt concept]
- Dacarbazine/Zorubicin [NCIt concept]
- ROAP Regimen [NCIt concept]
is_salt_form_of
- Zorubicin [NCIt concept]

Keyword's position in hierarchy(ies) :

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