" /> Flutemetamol F 18 - CISMeF





Preferred Label : Flutemetamol F 18;

NCIt synonyms : 2-[3-(18F)Fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol; Flutemetamol F-18; [18F]Flutemetamol; Fluorine F 18 Flutemetamol; [18F]FPIB; [18F]GE-067;

NCIt definition : A radiopharmaceutical containing flutemetamol, a thioflavin derivative of Pittsburgh compound B (PiB) labeled with the radioisotope fluorine F18 that can be used to detect beta-amyloid deposition upon positron emission tomography (PET). After intravenous administration of flutemetamol F 18, the flutemetamol moiety selectively accumulates in and binds to cerebral fibrillar amyloid-beta in the brain. The fluorine F18 radioisotope moiety is detected using PET, which allows imaging and quantification of amyloid-beta density. Amyloid plaque deposition is linked to cognitive decline, including Alzheimer's disease, and may be linked to chemotherapy-induced cognitive impairment (CICI).;

UNII : L49M066S0O;

InChIKey : VVECGOCJFKTUAX-HUYCHCPVSA-N;

CAS number : 765922-62-1;

Drug name : Vizamyl;

Chemical formula : C14H11FN2OS;

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31/05/2025


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