NCIt related terms : Co-Trimoxazole; Bactrim; Trimethoprim/Sulfamethoxazole (Bactrim DS);
NCIt definition : A synthetic combination of two antibacterial agents, trimethoprim and sulfamethoxazole.
This synergistic combination, also known as Co-Trimoxazole, inhibits two sequential
steps in the bacterial metabolism of folic acid. Trimethoprim is a pyrimidine inhibitor
of dihydrofolate reductase; sulfamethoxazole is a sulfamide inhibitor of bacterial
dihydrofolate synthase.;
Alternative definition : NCI-GLOSS: An antibiotic drug used to treat infection and prevent pneumocystis carinii
pneumonia.;
CAS number : 8064-90-2;
Drug name : Bactrim DS; Septra; Sulfamethoprim; Uroplus; Cotrim; Sulfatrim; Sulmeprim; Bactrim;
NSC code : 618652;
ChEBI ID : CHEBI:3770;
Codes from synonyms : NSC0618652; NSC0147832; CDR0000046089; CDR0000045244; 517; 3472;
Semantic type(s)