Trifluridine - CISMeF

Preferred Label : Trifluridine;

NCIt synonyms : Triflorothymidine; 2'-Deoxy-5-trifluoromethyluridine; F3TdR;

NCIt definition : A fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity. (NCI04);

UNII : RMW9V5RW38;

InChIKey : VSQQQLOSPVPRAZ-RRKCRQDMSA-N;

CAS number : 70-00-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 70-00-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C10H11F3N2O5;

NSC code : 75520;

Details

Origin ID

C905;

UMLS CUI

C0040987;

Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing trifluridine (medicinal product) [SNOMED CT concept]
- Trifluridine [ICD-11 Extension code]
- Trifluridine (substance) [SNOMED CT concept]
- trifluridine [ATC Code]
- trifluridine [Substance BNPC]
- trifluridine [MeSH concept]
- trifluridine [MeSH Descriptor]
- trifluridine [SNOMED Notion]
Validated automatic mappings to BTNT
- trifluridine [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Thymidylate Synthase [NCIt concept]

Keyword's position in hierarchy(ies) :

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