Preferred Label : PI3Ka/mTOR Inhibitor PKI-179;
NCIt related terms : PKI-179;
NCIt definition : A second generation, small-molecule mimetic of ATP that targets the mammalian target
of rapamycin (mTOR) with potential antineoplastic activity. PKI-179 selectively inhibits
mTOR and phosphoinositide-3-kinase (PI3K) alpha. By inhibiting the PI3K/mTOR signaling
pathway, this agent may inhibit tumor cell proliferation and survival.;
UNII : CNN7Y60164;
InChIKey : WXUUCRLKXQMWRY-OYRHEFFESA-N;
CAS number : 1197160-28-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1197160-28-3
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G-SRS /a ;
Molecule name : PKI-179;
Origin ID : C90291;
UMLS CUI : C4552050;
Semantic type(s)
- concept_is_in_subset
- has_target
