Uterine Corpus Undifferentiated Sarcoma

Preferred Label : Uterine Corpus Undifferentiated Sarcoma;

NCIt synonyms : Uterine Corpus Undifferentiated Endometrial Sarcoma;

NCIt related terms : Undifferentiated uterine sarcoma;

NCIt definition : A rare, high grade sarcoma that arises from the endometrial stroma or myometrium without a specific type of differentiation. It was previously also known as high grade endometrial stromal sarcoma. In 2014, high grade endometrial stromal sarcoma was reclassified and is currently considered a distinct and rare neoplasm. Undifferentiated uterine sarcoma has a worse prognosis.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL033042;

Details

Origin ID

C8972;

UMLS CUI

C2239246;

Currated CISMeF NLP mapping
- Endometrial stromal sarcoma, high grade (morphologic abnormality) [SNOMED CT concept]
Disease excludes normal cell origin
- Epithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
Excludes anatomical site(s)
- Bone [NCIt concept]
Has associated anatomic sites
- Connective and Soft Tissue [NCIt concept]
- Corpus Uteri [NCIt concept]
- Female Reproductive System [NCIt concept]
- Genitourinary System [NCIt concept]
- Reproductive System [NCIt concept]
- Uterus [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Endometrial stromal sarcoma, high grade (morphologic abnormality) [SNOMED CT concept]
- High grade endometrial stromal sarcoma (disorder) [SNOMED CT concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
disease_excludes_cytogenetic_abnormality
- t(10;17)(q22;p13) [NCIt concept]
- t(7;17)(p15;q21) [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Intermediate Filaments Present [NCIt concept]
- Intracytoplasmic Eosinophilic Inclusion [NCIt concept]
- Plexiform Vasculature Present [NCIt concept]
disease_excludes_molecular_abnormality
- JAZF1-SUZ12 Fusion Protein Expression [NCIt concept]
- YWHAE-FAM22 Fusion Protein Expression [NCIt concept]
disease_excludes_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Connective and Soft Tissue Cell [NCIt concept]
- Neoplastic Stromal Cell [NCIt concept]
disease_has_finding
- Aggressive Clinical Course [NCIt concept]
- High Grade Lesion [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Severe Cytologic Atypia [NCIt concept]
- Undifferentiated Lesion [NCIt concept]
disease_has_grade
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Connective and Soft Tissue Cell [NCIt concept]
- Endometrioid Stromal Cell [NCIt concept]
- Stromal Cell [NCIt concept]
disease_has_normal_tissue_origin
- Connective and Soft Tissue [NCIt concept]
- Soft Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Corpus Uteri [NCIt concept]
- Female Reproductive System [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 20q [NCIt concept]
- Gain of Chromosome 4q [NCIt concept]
- Gain of Chromosome 6q [NCIt concept]
- Gain of Chromosome 7p [NCIt concept]
- Gain of Chromosome 9q [NCIt concept]
- Loss of Chromosome 10p [NCIt concept]
- Loss of Chromosome 14q [NCIt concept]
- Loss of Chromosome 3q [NCIt concept]

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