t(7;17)(p15;q21)

Preferred Label : t(7;17)(p15;q21);

NCIt synonyms : t 7 17 p15 q21;

NCIt definition : A chromosomal translocation involving breakpoints within the p15 band on the short arm of chromosome 7 and the q21 band on the long arm of chromosome 17. This rearrangement is associated with JAZF1-SUZ12 fusion gene expression and endometrial stromal sarcoma.;

NCIt note : The Atlas of Genetics and Cytogenetics in Oncology and Haematology designates t(7;17)(p15;q11) as the breakpoints of the JAZF1-SUZ12 fusion.;

PubMed : 27219024;

Details

Origin ID

C40160;

UMLS CUI

C1515785;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
cytogenetic_abnormality_involves_chromosome
- Human Chromosome 17 [NCIt concept]
- Human Chromosome 7 [NCIt concept]
is_not_cytogenetic_abnormality_of_disease
- Uterine Corpus Tumor Resembling Ovarian Sex Cord Tumor [NCIt concept]
- Uterine Corpus Undifferentiated Sarcoma [NCIt concept]
may_be_cytogenetic_abnormality_of_disease
- Endometrial Stromal Nodule [NCIt concept]
- Uterine Corpus Low Grade Endometrial Stromal Sarcoma [NCIt concept]
molecular_abnormality_involves_gene
- JAZF1 Gene [NCIt concept]
- JAZF1/SUZ12 Fusion Gene [NCIt concept]
- SUZ12 Gene [NCIt concept]

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