Refractory Primary Mediastinal Large B-Cell Lymphoma

Preferred Label : Refractory Primary Mediastinal Large B-Cell Lymphoma;

NCIt synonyms : Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Refractory Mediastinal Thymic Large B-Cell Cell Lymphoma;

NCIt related terms : Refractory Mediastinal (Thymic) Large B-Cell Lymphoma;

NCIt definition : Primary mediastinal large B-cell lymphoma that is resistant to treatment.;

Neoplastic status : Malignant;

Details

Origin ID

C8875;

UMLS CUI

C0855154;

Currated CISMeF NLP mapping
- Large B-cell lymphoma subtype primary mediastinal (Thymic) large B-cell lymphoma refractory [MedDRA LLT]
- Primary mediastinal large B-cell lymphoma refractory [MedDRA Preferred Term]
Disease excludes abnormal cell
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- CD30-Positive Neoplastic Cells Present [NCIt concept]
- Localized Disease [NCIt concept]
- Lymphadenopathy [NCIt concept]
- Rapidly Enlarging Mass [NCIt concept]
Excludes anatomical site(s)
- Neck [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
- Mediastinum [NCIt concept]
- Respiratory System [NCIt concept]
- Thoracic Cavity [NCIt concept]
- Thymus Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Large B-cell lymphoma subtype primary mediastinal (Thymic) large B-cell lymphoma refractory [MedDRA LLT]
- Primary mediastinal large B-cell lymphoma refractory [MedDRA Preferred Term]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_excludes_molecular_abnormality
- Clonal BCL2 Gene Rearrangement [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Large B-Lymphocyte [NCIt concept]
- Neoplastic Large B-Lymphocyte with Pale Cytoplasm [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Diffuse Pattern [NCIt concept]
- Fibrosis [NCIt concept]
- Increased NFkappaB Pathway Activation [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Refractory Disease [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
- Thymic B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
- Thymic Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
- Mediastinum [NCIt concept]
- Thymus Gland [NCIt concept]
disease_mapped_to_chromosome
- Human Chromosome 9 [NCIt concept]
disease_may_have_associated_disease
- Superior Vena Cava Syndrome [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 9p [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]
- PDCD1LG2 Gene Overexpression [NCIt concept]

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