Preferred Label : Tasisulam Sodium;
NCIt synonyms : Benzamide, N-[(5-Bromo-2-thienyl)sulfonyl]-2,4-dichloro-, Sodium Salt;
NCIt definition : The sodium salt of an acyl-sulfonamide with potential antineoplastic activity. Selectively
toxic towards tumor cells, tasisulam appears to induce tumor cell apoptosis by a mitochondrial-targeted
mechanism involving the loss of mitochondrial membrane potential and induction of
reactive oxygen species (ROS). In combination with an angiogenesis inhibitor, this
agent may exhibit synergistic antiangiogenic activity.;
UNII : O3955SHR9J;
InChIKey : JCOHXVDKRMWUQP-UHFFFAOYSA-M;
CAS number : 519055-63-1;
Molecule name : LY573636-Sodium; LY-573636.Na;
Chemical formula : C11H5BrCl2NO3S2.Na;
PubMed : 18949427;
Origin ID : C88304;
UMLS CUI : C2981821;
Semantic type(s)
- concept_is_in_subset
