Fexagratinib - CISMeF

Preferred Label : Fexagratinib;

NCIt synonyms : FGFR Inhibitor AZD4547;

NCIt definition : An orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. fexagratinib binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. FGFR, up-regulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cellular proliferation, differentiation and survival.;

UNII : 2167OG1EKJ;

CAS number : 1035270-39-3;

Molecule name : AZD4547; ABSK-091; KB-74810;

NCI Metathesaurus CUI : CL412460;

ChEBI ID : CHEBI:63453;

Details

Origin ID

C88272;

UMLS CUI

C2981795;

Currated CISMeF NLP mapping
- AZD4547 [MeSH concept]
- AZD4547 [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- AZD4547 [MeSH Supplementary Concept]
- AZD4547 [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Fibroblast Growth Factor Receptor Family [NCIt concept]

Keyword's position in hierarchy(ies) :

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