Golimumab - CISMeF

Preferred Label : Golimumab;

NCIt synonyms : Immunoglobulin G1, Anti-(Human Tumor Necrosis Factor Alpha) (Human Monoclonal CNTO 148 Gamma-1-Chain), Disulfide with Human Monoclonal CNTO 148 Kappa-Chain, Dimer;

NCIt definition : A human monoclonal antibody directed against the pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-a) with immunosuppressive activity. Golimumab binds to TNF-a, thereby preventing TNF-a-mediated immune responses. TNF-a production is dysregulated in various auto-immune diseases and in cancer.;

UNII : 91X1KLU43E;

CAS number : 476181-74-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 476181-74-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : CNTO 148;

Details

Origin ID

C87766;

UMLS CUI

C2353893;

Automatic exact mappings (from CISMeF team)
- Golimumab [ICD-11 Extension code]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Golimumab [Substance BNPC]
- Golimumab [LOINC component]
- Golimumab (substance) [SNOMED CT concept]
- Product containing golimumab (medicinal product) [SNOMED CT concept]
- golimumab [ATC Code]
- golimumab [International Nonproprietary Name]
- golimumab [MeSH concept]
- golimumab [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- golimumab [ATC Code]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Tumor Necrosis Factor [NCIt concept]

Keyword's position in hierarchy(ies) :

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