Aprosulate - CISMeF

Preferred Label : Aprosulate;

NCIt synonyms : N,N'-Trimethylenebis(Actobionamide) Hexadecakis Sulfate (Ester);

NCIt definition : A synthetic sulfated bis(lactobionic acid amide) derivative and heparin analogue with anticoagulant activity. Aprosulate is made up of two fully sulfated lactobionic acid moieties with a diamine spacer via two amide bonds. This agent inhibits thrombin by antagonizing heparin cofactor II (HCII) and thus prevents thrombin-induced platelet aggregation. It prolongs clotting time.;

UNII : X94B38CQOM;

InChIKey : KSXQTGMWWMBCIP-VXMGFIRPSA-N;

CAS number : 123123-68-2;

Chemical formula : C27H50N2O70S16;

Details

Origin ID

C87428;

UMLS CUI

C0103894;

Currated CISMeF NLP mapping
- aprosulate [MeSH concept]
- aprosulate [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- aprosulate [MeSH Supplementary Concept]
- aprosulate [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Aprosulate Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Aprosulate Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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