Preferred Label : Aprosulate Sodium;
NCIt synonyms : D-Gluconamide, N,N'-1,3-propanediylbis(4-O-(2,3,4,6-tetra-O-sulfo-beta-D-galactopyranosyl))-,
2,2',3,3',5,5',6,6'-octakis(hydrogen sulfate), Hexadecasodium Salt; N,N'-Trimethylenebis(actobionamide) Hexadecakis(Sodium Sulfate) (Ester);
NCIt definition : The sodium salt form of aprosulate, a synthetic sulfated bis(lactobionic acid amide)
derivative and heparin analogue with anticoagulant activity. Aprosulate is made up
of two fully sulfated lactobionic acid moieties with a diamine spacer via two amide
bonds. This agent inhibits thrombin by antagonizing heparin cofactor II (HCII) and
thus blocking thrombin-induced platelet aggregation. It prolongs clotting time.;
UNII : 311154J4LN;
InChIKey : CXKOATPJKFZCEL-HPXJARCXSA-A;
CAS number : 123072-45-7;
Chemical formula : C27H34N2O70S16.16Na;
Origin ID : C77990;
UMLS CUI : C2698176;
Semantic type(s)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
