Thiamine - CISMeF

Preferred Label : Thiamine;

NCIt synonyms : B1 Vitamin; Vitamin-B1; 2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1-thia-3-azoniacyclopenta-2,4-dien-5-yl]ethanol; Vit B1;

NCIt related terms : Thiamin; Vitamin B1; Aneurin;

NCIt definition : A heat-labile and water-soluble essential vitamin, belonging to the vitamin B family, with antioxidant, erythropoietic, mood modulating, and glucose-regulating activities. Thiamine reacts with adenosine triphosphate (ATP) to form an active coenzyme, thiamine pyrophosphate. Thiamine pyrophosphate is necessary for the actions of pyruvate dehydrogenase and alpha-ketoglutarate in carbohydrate metabolism and for the actions of transketolase, an enzyme that plays an important role in the pentose phosphate pathway. Thiamine plays a key role in intracellular glucose metabolism and may inhibit the action of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine may also protect against lead toxicity by inhibiting lead-induced lipid peroxidation.;

Alternative definition : NCI-GLOSS: A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Vitamin B1 helps some enzymes work properly, helps break down sugars in the diet, and keeps nerves and the heart healthy. It is found in pork, organ meats, peas, beans, nuts, and whole grains. Vitamin B1 is water-soluble (can dissolve in water) and must be taken in daily. Not enough vitamin B1 can cause a disease called beriberi (a condition marked by heart, nerve, and digestive disorders). Too much vitamin B1 may help cancer cells grow faster.; CRCH: Water-soluble vitamin that is a coenzyme in the metabolism of carbohydrates and branched-chain amino acids. (DRI);

UNII : X66NSO3N35;

InChIKey : MYVIATVLJGTBFV-UHFFFAOYSA-M;

CAS number : 59-43-8;

Unit used : mg;

Chemical formula : C12H17N4OS.Cl;

ChEBI ID : CHEBI:33283;

Codes from synonyms : 05001; CDR0000556404; CDR0000629163;

Details

Origin ID

C874;

UMLS CUI

C0039840;

Currated CISMeF NLP mapping
- Aneurine [ICD-11 Extension code]
- Thiamine [PASCAL descriptor]
- Thiamine [ICD-11 Extension code]
- Thiamine [SMS substance]
- Thiamine [LOINC component]
- Thiamine [MedDRA LLT]
- Thiamine (substance) [SNOMED CT concept]
- Vitamin B1 [ICD-11 Extension code]
- Vitamin B1 [LOINC component]
- Vitamin B1 [ICHI extension code]
- Vitamin B1 [MedDRA Preferred Term]
- thiamine [Substance BNPC]
- thiamine [MeSH Descriptor]
- thiamine [MeSH concept]
- thiamine [SNOMED Notion]
- vitamin B1 [Artificial nutrition thesaurus concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
- Vitamin [UMLS semantic type]
UMLS correspondences (same concept)
- Aneurine [ICD-11 Extension code]
- Product containing thiamine (medicinal product) [SNOMED CT concept]
- Thiamine [LOINC component]
- Thiamine (substance) [SNOMED CT concept]
- Vitamin B1 [LOINC component]
- thiamine [MeSH concept]
- thiamine [MeSH Descriptor]
- thiamine [SNOMED Notion]
- thiamine (vit b1) [ATC Code]
- thiamine preparation [SNOMED Notion]
Validated automatic mappings to BTNT
- thiamine (vit b1) [ATC Code]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Thiamine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Thiamine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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