NCIt definition : The potassium salt form of propicillin, a semisynthetic acid-stable penicillin with
antibacterial activity. Propicillin binds to and inactivates penicillin-binding proteins
(PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs
interferes with the cross-linkage of peptidoglycan chains necessary for bacterial
cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and
results in the weakening of the bacterial cell wall, eventually causing cell lysis.;