NCIt definition : A semisynthetic, acid stable, penicillin with antibacterial activity. Propicillin
binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane
of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage
of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This
interrupts bacterial cell wall synthesis and results in the weakening of the bacterial
cell wall and causes cell lysis.;