" /> Tinzaparin - CISMeF





Preferred Label : Tinzaparin;

NCIt definition : A low molecular weight heparin (LMWH), obtained by controlled enzymatic depolymerization of heparin from porcine intestinal mucosa, with antithrombotic properties. Tinzaparin is a potent inhibitor of several activated coagulation factors, especially Factors Xa and IIa (thrombin); its primary activity is mediated through the plasma protease inhibitor antithrombin. In addition, this agent may inhibit angiogenesis through: 1) competitive binding of the heparin-binding sites on endothelial cells for the proangiogenic cytokines vascular endothelial growth factor (VEGF) and beta-fibroblast growth factor (beta-FGF) and 2) increasing the release of tissue factor pathway inhibitor (TFPI), a negative regulator of angiogenesis.;

Alternative definition : NCI-GLOSS: A drug that is used with another drug, warfarin, to treat blood clots that form deep in the veins and to prevent new blood clots from forming. It is a type of anticoagulant.;

UNII : 7UQ7X4Y489;

CAS number : 9005-49-6;

Molecule name : B01AB10;

Chemical formula : (C14H18NO11)n.2(C12H16NO13S)n.3HO3S;

ChEBI ID : CHEBI:28304;

Codes from synonyms : CDR0000471773; 495;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
04/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.