" /> Tinzaparin - CISMeF





Preferred Label : Tinzaparin;

NCIt definition : A low molecular weight heparin (LMWH), obtained by controlled enzymatic depolymerization of heparin from porcine intestinal mucosa, with antithrombotic properties. Tinzaparin is a potent inhibitor of several activated coagulation factors, especially Factors Xa and IIa (thrombin); its primary activity is mediated through the plasma protease inhibitor antithrombin. In addition, this agent may inhibit angiogenesis through: 1) competitive binding of the heparin-binding sites on endothelial cells for the proangiogenic cytokines vascular endothelial growth factor (VEGF) and beta-fibroblast growth factor (beta-FGF) and 2) increasing the release of tissue factor pathway inhibitor (TFPI), a negative regulator of angiogenesis.;

Alternative definition : NCI-GLOSS: A drug that is used with another drug, warfarin, to treat blood clots that form deep in the veins and to prevent new blood clots from forming. It is a type of anticoagulant.;

UNII : 7UQ7X4Y489;

CAS number : 9005-49-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 9005-49-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : B01AB10;

Chemical formula : (C14H18NO11)n.2(C12H16NO13S)n.3HO3S;

ChEBI ID : CHEBI:28304;

Codes from synonyms : CDR0000471773; 495;

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21/05/2024


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