Tetracycline - CISMeF

Preferred Label : Tetracycline;

NCIt synonyms : 4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide; TCN;

NCIt definition : A broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline binds to the 30S ribosomal subunit, interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis.;

Alternative definition : NCI-GLOSS: A drug used to treat bacterial infections. It stops the growth of bacteria by keeping them from making proteins. Tetracycline also binds to new bone tissue and is being studied as a way to detect bone growth. Tetracycline is a type of antibiotic and a type of bone-labeling agent.;

UNII : F8VB5M810T;

CAS number : 60-54-8;

Chemical formula : C22H24N2O8;

NSC code : 108579;

ChEBI ID : CHEBI:27902;

Codes from synonyms : CDR0000045448; 03341; 27930;

Details

Origin ID

C865;

UMLS CUI

C0039644;

False automatic mappings
- Tetracyclines [ICD-10 Sub-category (who)]
- Tetracyclines [ICD-10 Sub-category (who)]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing tetracycline (medicinal product) [SNOMED CT concept]
- Tetracycline [LOINC component]
- Tetracycline (substance) [SNOMED CT concept]
- tetracycline [ATC Code]
- tetracycline [ATC Code]
- tetracycline [ATC Code]
- tetracycline [ATC Code]
- tetracycline [ATC Code]
- tetracycline [ATC Code]
- tetracycline [MeSH Descriptor]
- tetracycline [MeSH concept]
- tetracycline, nos [SNOMED Notion]
Validated automatic mappings to BTNT
- tetracycline [ATC Code]
- tetracycline [ATC Code]
- tetracycline [ATC Code]
- tetracycline [ATC Code]
- tetracycline [ATC Code]
- tetracycline [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
has_salt_form
- Tetracycline Calcium [NCIt concept]
- Tetracycline Hydrochloride [NCIt concept]
is_component_of_chemotherapy_regimen
- Bismuth Subcitrate/Metronidazole/Omeprazole/Tetracycline [NCIt concept]
- Rifampin/Tetracycline [NCIt concept]
is_free_acid_or_base_form_of
- Tetracycline Calcium [NCIt concept]
- Tetracycline Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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