Preferred Label : Tetracycline Hydrochloride;
NCIt synonyms : (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
Monohydrochloride;
NCIt related terms : Achromycin;
NCIt definition : The hydrochloride salt of tetracycline, a broad-spectrum naphthacene antibiotic produced
semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium
Streptomyces aureofaciens. In bacteria, tetracycline blocks binding of aminoacyl-tRNA
to the mRNA-ribosome complex, thereby inhibiting protein synthesis and bacterial cell
growth. Because naturally fluorescing tetracycline binds to newly formed bone at the
bone/osteoid interface, tetracycline-labeling of bone and fluorescence microscopy
may be used to perform bone histomorphometry.;
UNII : P6R62377KV;
InChIKey : XMEVHPAGJVLHIG-FMZCEJRJSA-N;
CAS number : 64-75-5;
Drug name : Achromycin; Tetracyn; Sumycin; Panmycin;
Chemical formula : C22H24N2O8.HCl;
Codes from synonyms : NSC0108579;
Origin ID : C48020;
UMLS CUI : C0546879;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
