" /> Onvitrelin Ucalontide - CISMeF





Preferred Label : Onvitrelin Ucalontide;

NCIt synonyms : Membrane-Disrupting Peptide EP-100;

NCIt definition : A water-soluble, positively charged fusion protein consisting of a luteinizing hormone releasing hormone (LHRH) receptor-targeting ligand conjugated to the membrane-disrupting peptide CLIP 71 with membrane-disrupting and potential antineoplastic activities. The LHRH ligand moiety of onvitrelin ucalontide specifically binds to LHRH receptors, which are upregulated on a variety of human cancer cell types. Subsequently, the positively charged CLIP 71 moiety of this agent interacts with the negatively charged membrane on the cancer cell surface, which may result in cell membrane disruption and cell lysis.;

UNII : UF1EL37E41;

CAS number : 1620643-19-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1620643-19-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : EP-100;

NCI Metathesaurus CUI : CL412421;

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Keyword's position in hierarchy(ies) : arborescence

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15/05/2024


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