Topoisomerase I Inhibitor Genz-644282

Preferred Label : Topoisomerase I Inhibitor Genz-644282;

NCIt related terms : GENZ-644282;

NCIt definition : A non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz-644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single-strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations.;

UNII : 717I541I2R;

CAS number : 529488-28-6;

Molecule name : Genz-644282;

Details

Origin ID

C84851;

UMLS CUI

C2827528;

Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Genz-644282 [MeSH Supplementary Concept]
- Genz-644282 [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- DNA Topoisomerase 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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