Preferred Label : PAK4 Inhibitor PF-03758309;
NCIt related terms : PF-03758309;
NCIt definition : An orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with
potential antineoplastic activity. PAK4 inhibitor PF-03758309 binds to PAK4, inhibiting
PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to
the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer
cell types and plays an important role in cancer cell motility, proliferation, and
survival.;
UNII : PK459EA5I2;
CAS number : 898044-15-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 898044-15-0
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Molecule name : PF-03758309;
NCI Metathesaurus CUI : CL412392;
Origin ID : C84841;
UMLS CUI : C2827519;
Semantic type(s)
- concept_is_in_subset
- has_target
