" /> APOE wt Allele - CISMeF





Preferred Label : APOE wt Allele;

NCIt synonyms : Alzheimer Disease 2 (APOE*E4-Associated, Late Onset) Gene; LPG; Apolipoprotein E wt Allele; MGC1571; AD2; LDLCQ5; ApoE3; APOE*E3; APOE*3 Allele; APOE-epsilon3 Allele;

NCIt definition : Human APOE wild-type allele is located in the vicinity of 19q13.2 and is approximately 4 kb in length. This allele, which encodes apolipoprotein E protein, plays a role in the mediation of lipid transport and metabolism. Genetic variation is involved in both cardiovascular disease and Alzheimer's disease. Mutation of the gene is associated with type III hyperlipoproteinemia.;

NCIt note : The APOE wild-type allele is characterized by a thmine at position 388 and a cytosine at position 526, which is also called the APOE*3 allele.;

GenBank Accession Number : K00396;

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16/05/2024


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