CLU wt Allele - CISMeF

Preferred Label : CLU wt Allele;

NCIt synonyms : SP-40; SGP-2; Clusterin (Complement Lysis Inhibitor, SP-40,40, Sulfated Glycoprotein 2, Testosterone-Repressed Prostate Message 2, Apolipoprotein J) Gene; KUB1; Clusterin wt Allele; SGP2; Testosterone-Repressed Prostate Message 2 Gene; TRPM-2; APOJ; MGC24903; Sulfated Glycoprotein 2 Gene; Complement Lysis Inhibitor Gene; TRPM2; Apolipoprotein J Gene; AAG4; CLI;

NCIt definition : Human CLU wild-type allele is located within 8p21-p12 and is approximately 36 kb in length. This allele, which encodes clusterin protein, may play a role in the modulation of complement activation, lipid metabolism and apoptosis. Genetic variation may play a role in Alzheimer's disease.;

GenBank Accession Number : M64722;

Details

Origin ID

C84430;

UMLS CUI

C2827446;

OMIM relation
- Clusterin [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Alzheimer's Disease [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 8p21-p12 [NCIt concept]
gene_is_element_in_pathway
- Classical Complement Pathway [NCIt concept]
gene_plays_role_in_process
- Complement Activation [NCIt concept]
- Ligand Binding [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients