" /> Streptonigrin - CISMeF





Preferred Label : Streptonigrin;

NCIt synonyms : STN; Rufocromomycin; 5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-2-pyridinecarboxylic Acid; 5-Amino-6-(70-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic Acid;

NCIt related terms : Bruneomycin;

NCIt definition : An aminoquinone antineoplastic antibiotic isolated from the bacterium Streptomyces flocculus. Streptonigrin complexes with DNA and topoisomerase II, resulting in DNA cleavage and inhibition of DNA replication and RNA synthesis. This agent also acts as a reverse transcriptase inhibitor and causes free radical-mediated cellular damage. (NCI04);

UNII : 261Q3JB310;

InChIKey : PVYJZLYGTZKPJE-UHFFFAOYSA-N;

CAS number : 3930-19-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 3930-19-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : PC-501; BA-163;

Chemical formula : C25H22N4O8;

NSC code : 83950; 45383;

ChEBI ID : CHEBI:9287;

Codes from synonyms : NSC0045383; 31698; NSC0083950;

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12/05/2024


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