streptonigrin - CISMeF

Preferred Label : streptonigrin;

MeSH definition : Complex cytotoxic antibiotic obtained from Streptomyces flocculus or S. rufochronmogenus. It is used in advanced carcinoma and causes leukopenia.;

MeSH synonym : rufocromomycin; bruneomycin; brunemycin;

MeSH hyponym : NSC-45383; nigrin; NSC 45383; NSC45383;

MeSH CAS label : 2-Pyridinecarboxylic acid, 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-;

MeSH Related Number : 3930-19-6 (Streptonigrin);

Registry Number MeSH : 3930-19-6;

Wikipedia link : https://en.wikipedia.org/wiki/Streptonigrin;

Codes EINECS : 223-501-8;

Is substance : O;

UNII : 261Q3JB310;

InChIKey : PVYJZLYGTZKPJE-UHFFFAOYSA-N;

Details

Origin ID

D013308;

UMLS CUI

C0038427;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- rufocromomycin [Substance BNPC]
Currated CISMeF NLP mapping
- Rufocromomycin [ICD-11 Extension code]
- Streptonigrin [NCIt concept]
Pharmacological action(s)
- antibiotics, antineoplastic [MeSH Descriptor]
Record concept(s)
- NSC-45383 [MeSH concept]
- nigrin [MeSH concept]
- streptonigrin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 10'-O-demethylstreptonigrin [MeSH Supplementary Concept]
- 10'-desmethoxystreptonigrin [MeSH Supplementary Concept]
- 2'-decarboxy-2'-aminostreptonigrin [MeSH Supplementary Concept]
- 7-(1-methyl-2-oxopropyl)streptonigrin [MeSH Supplementary Concept]
- decarboxy-2'-(hydroxymethyl)-demethyllavendamycin [MeSH Supplementary Concept]
- di-2',8'-O-di-5',5'-N,N-methylstreptonigrone [MeSH Supplementary Concept]
- lavendamycin [MeSH Supplementary Concept]
- retrostatin [MeSH Supplementary Concept]
- streptonigrone [MeSH Supplementary Concept]
- tri-1',5',5'-N,N,N-mono-8'-O-methylstreptonigrone [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Rufocromomycin [ICD-11 Extension code]
- Streptonigrin [NCIt concept]
- rufocromomycin [Substance BNPC]

Keyword's position in hierarchy(ies) :

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