" /> Inecalcitol - CISMeF





Preferred Label : Inecalcitol;

NCIt synonyms : (7E)-19-Nor-9,10-seco-14beta-cholesta-5,7-dien-23-yne-1alpha,3beta,25-triol; ICC;

NCIt definition : An analog of calcitriol and a vitamin D3 receptor (VDR) agonist, with potential antineoplastic activity. Upon administration, inecalcitol targets and binds to VDR. This activates VDR and VDR-mediated signal transduction pathways. This modulates the VDR-mediated expression of certain genes, including the expression of anti-cancer genes, enhances cellular differentiation, induces tumor cell apoptosis and inhibits tumor cell growth. VDR plays a central role in calcium homeostasis and in the growth of certain cancer cells.;

UNII : 05FZV98342;

InChIKey : HHGRMHMXKPQNGF-WNSNRMDMSA-N;

CAS number : 163217-09-2;

Molecule name : TX 522;

Chemical formula : C26H40O3;

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27/07/2025


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