Preferred Label : Davalintide Acetate;
NCIt synonyms : L-Tyrosinamide, L-Lysyl-L-Cysteinyl-L-Asparaginyl-L-Threonyl-L-Alanyl-L-Threonyl-L-Cysteinyl-L-Valyl-L-Leucylglycyl-L-Arginyl-L-Leucyl-L-Seryl-L-Glutaminyl-L-Alpha-Glutamyl-L-Leucyl-L-Histidyl-L-Arginyl-L-Leucyl-L-Glutaminyl-L-Threonyl-L-Tyrosyl-L-Proly
Acetate; L-Lysyl-Des-2-L-Serine-(4-L-Threonine(Lt), 5-L-Alanine(Sa),11-L-Arginine(Kr),18-L-Arginine(Kr),30-L-Asparagine(Gn),32-L-Tyrosine(Py))Calcitonin-1
Oncorhynchus Keta (Chum Salmon), Calcitonin-1 Precursor-(83-114)-Peptidamide Acetate
Salt;
NCIt definition : The acetate salt form of davalintde, a second-generation, 32-amino acid peptide analogue
of human amylin with antihyperglycemic activity. By mimicking amylin, davalintide,
which has a half-life similar to amylin, slows gastric emptying, inhibits digestive
secretions (gastric acid, pancreatic enzymes, and bile), reduces glucagon secretion,
and increases satiety. These actions results in a decrease in blood glucose levels.
Furthermore, davalintide exhibits high affinity binding to amylin, calcitonin and
calcitonin-related peptide receptors. Compared to amylin, davalintide shows a prolonged
duration of action due to its slowed receptor dissociation.;
UNII : 4QM48103XT;
CAS number : 879197-42-9;
Chemical formula : C152H248N50O49S2.C2H4O2;
Origin ID : C83651;
UMLS CUI : C2827126;
Semantic type(s)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
