Preferred Label : Davalintide;
NCIt synonyms : L-Tyrosinamide, L-Lysyl-L-Cysteinyl-L-Asparaginyl-L-Threonyl-L-Alanyl-L-Threonyl-L-Cysteinyl-L-Valyl-L-Leucylglycyl-L-Arginyl-L-Leucyl-L-Seryl-L-Glutaminyl-L-Alpha-Glutamyl-L-Leucyl-L-Histidyl-L-Arginyl-L-Leucyl-L-Glutaminyl-L-Threonyl-L-Tyrosyl-L-Proly; L-Lysyl-Des-2-L-Serine-(4-L-Threonine(Lt),5-L-Alanine(Sa),11-L-Arginine(Kr),18-L-Arginine(Kr),30-L-Asparagine(Gn),32-L-Tyrosine(Py))Calcitonin-1
Oncorhynchus Keta (Chum Salmon), Calcitonin-1 Precursor-(83-114)-Peptidamide;
NCIt definition : A second-generation, 32-amino acid peptide analogue of human amylin with antihyperglycemic
activity. By mimicking amylin, davalintide, which has a half-life similar to amylin,
slows gastric emptying, inhibits digestive secretions (gastric acid, pancreatic enzymes,
and bile), reduces glucagon secretion, and increases satiety. These actions result
in a decrease in blood glucose levels. Furthermore, davalintide exhibits high affinity
binding to amylin, calcitonin and calcitonin-related peptide receptors. Compared to
amylin, davalintide shows a prolonged duration of action due to its slowed receptor
dissociation.;
UNII : 668U999F9T;
CAS number : 863919-85-1;
Molecule name : AC2307;
Chemical formula : C152H248N50O49S2;
Origin ID : C83650;
UMLS CUI : C2827125;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_salt_form
- is_free_acid_or_base_form_of
