Preferred Label : Besifloxacin;
NCIt synonyms : ( )-7-((3R)-3-Aminohexahydro-1H-Azepin-1-yl)-8-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic
Acid; 3-Quinolinecarboxylic Acid, 7-((3R)-3-Aminohexahydro-1H-Azepin-1-yl)-8-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-;
NCIt definition : A synthetic fourth-generation fluoroquinolone antibiotic, with broad spectrum antibacterial
activity. Upon administration, besifloxacin targets, binds to and inhibits both bacterial
DNA gyrase, an enzyme essential for DNA replication, transcription and repair of bacterial
DNA, and bacterial topoisomerase IV, an enzyme required for partitioning of the chromosomal
DNA during bacterial cell division. This inhibits DNA replication, transcription,
and repair and cell division.;
UNII : BFE2NBZ7NX;
InChIKey : QFFGVLORLPOAEC-SNVBAGLBSA-N;
CAS number : 141388-76-3;
Chemical formula : C19H21ClFN3O3;
Origin ID : C83553;
UMLS CUI : C2351042;
Currated CISMeF NLP mapping
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- has_salt_form
- is_free_acid_or_base_form_of
