Preferred Label : Besifloxacin Hydrochloride;
NCIt synonyms : ( )-7-((3R)-3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic
Acid Hydrochloride;
NCIt definition : The hydrochloride salt form of besifloxacin, a synthetic fourth-generation fluoroquinolone
antibiotic, with broad spectrum antibacterial activity. Upon administration, besifloxacin
targets, binds to and inhibits both bacterial DNA gyrase, an enzyme essential for
DNA replication, transcription and repair of bacterial DNA, and bacterial topoisomerase
IV, an enzyme required for partitioning of the chromosomal DNA during bacterial cell
division. This inhibits DNA replication, transcription, and repair and cell division.;
UNII : 7506A6J57T;
InChIKey : PMQBICKXAAKXAY-HNCPQSOCSA-N;
CAS number : 405165-61-9;
Drug name : Besivance;
Molecule name : BOL-303224-A; SS734;
Chemical formula : C19H21ClFN3O3.HCl;
Origin ID : C76228;
UMLS CUI : C2702050;
Currated CISMeF NLP mapping
- Semantic type(s)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
